COMPARISON OF OVERALL SENSITIVITY AND SPECIFICITY ACROSS DIFFERENT NEWBORN SCREENING ALGORITHMS FOR CONGENITAL CYTOMEGALOVIRUS

Comparison of Overall Sensitivity and Specificity across Different Newborn Screening Algorithms for Congenital Cytomegalovirus

Screening newborns for congenital cytomegalovirus (cCMV) infection is critical for early detection and prompt diagnosis of related long-term consequences of infection, such as sensorineural hearing loss and neurodevelopmental delays.The objective of this study was to describe the validity of different newborn cCMV infection screening approaches and

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Pharmacological and Biological Targeting of FGFR1 in Cancer

FGFR1 is a key member of the fibroblast growth factor receptor family, mediating critical signaling pathways such as RAS-MAPK and PI3K-AKT.which are integral to regulating essential cellular processes, including proliferation, differentiation, and survival.Alterations in FGFR1 can lead to constitutive activation of signaling pathways that drive onc

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Analysis of Stress-Strain State and Contact Pressures on Surfaces of Kaplan Runner Blade Bearing Bronze Bushes

An analysis of the existing and prospective blade seal designs for Kaplan runners was performed.The selected design type provides the maximum ecological safety for Kaplan runners.A 3D model of runner hub sector with the trunnion, inner and outer bushes of blade trunnion was generated taking into account the cyclic symmetry of the runner design base

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